Video Library
Running time: 58 minutes, 46 seconds
01.28 Concept of cumulated LDL exposure (mg-years)
05.11 Re-defining secondary prevention
08.04 Early secondary prevention
11.27 Late secondary prevention (CHD)
19.17 Late secondary prevention (PAD)
20.15 Very late secondary prevention (ACS)
23.18 Longer is better
24.55 Earlier is better
26.21 Younger is better
28.39 Older Adults also deserve treatment
41.12 Audience Q&A
Video Library
“Lower, Longer, Sooner, Earlier, and Younger”: Do we have enough evidence?
Prof. Chiang discusses Atherosclerotic Cardiovascular Disease (ASCVD) in context of cumulated LDL exposure, and the different stages of secondary prevention and how starting to manage the disease at a younger age or earlier stage is beneficial. At 41:12 he answers audience questions.
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Case Studies
August 2023
Take this short quiz to test your knowledge on the recently published debate on dyslipidemias titled “Great debate: lipid-lowering therapies should be guided by vascular imaging rather than by circulating biomarkers”.
CLICK HERE TO VIEW THE DEBATE.
Eur Heart J. 2023 Jul 1;44(25):2292-2304. doi: 10.1093/eurheartj/ehad275
Case Studies
Quiz of the month – April 2023
Take our patient case study quiz specially curated for you by our Faculty Member, Prof. Samer Ellahham.
Case Study: A 65-year-old man with a history of dyslipidemia, type 2 diabetes mellitus and systemic hypertension.
Presentation:
New onset crescendo angina x 5 days culminating
Rest pain for the past 2h
No history of other vascular events or heart attack, no TIA or stroke
Weight: 90 kg
Exam: BP 150/85 (slightly elevated), Heart Rate 80
No murmur detected
Medication:
Valsartan 160 mg daily, Aspirin 81 mg daily, Rosuvastatin 10 mg daily, Metformin 500 mg twice daily
Labs:
BMI 31kg/m2, waist circumference 101.6 cm (40 inches), (-) tobacco (quit last year – 60-pack-year history)
Normal CBC, electrolytes
Troponin: Elevated
Electrocardiogram:1-2 mm horizontal ST depression infero-lateral leads
Chest X-ray: Normal
Lipid panel:
Total cholesterol (TC) 192 mg/dL
HDL-C 46 mg/dL
Triglycerides 180 mg/dL (non-fasting)
LDL-C 110 mg/dL
Non-HDL-C 146 mg/ dL
What are the first impressions about this patient?
Case Studies
Quiz of the month – February 2023
Take our patient case study quiz specially curated for you by our Faculty Member, Prof. Stephen Nicholls.
Case Study: A 58-year-old overweight man with a 10-year history of primary hypercholesterolemia presents for a checkup. At diagnosis of hypercholesterolemia, his LDL-C was 198 mg/dL; his clinician recommended diet and exercise interventions and started atorvastatin 10 mg qd. The patient follows a low saturated-fat diet and exercises daily. However, he could not tolerate higher doses of atorvastatin or rosuvastatin 5 mg or pravastatin 20 mg. Today, his LDL-C is 138 mg/dL, HDL-C 52 mg/dL, and triglycerides 78 mg/dL. He continues to take atorvastatin 10 mg qd.
You add ezetimibe, and follow-up bloods a month later show an LDL-C of 108 mg/dl. You are not sure if he has ASCVD, so review of prior imaging shows he had a CT scan a year ago to evaluate shortness of breath, and the report comments that he has “moderate coronary artery calcification”. You check and Lp(a) and it is elevated at 200 nmol/L (upper limit of normal is 75 nmol/L).
