The first part of this two-part webinar features key highlights from the ESC Congress 2025. Prof. Deepak Bhatt provides an in-depth analysis of several significant trials, including DAPA-ACT, BETAMI-DANBLOCK, REBOOT-CNIC, PANTHER, VICTORIAN-Difference, NEWTON-CABG CardioLink-5, and REDUCE-IT. Moreover, he explores critical aspects of dyslipidaemia, drawing from the 2025 focused update guideline published by the ESC. The second part of the webinar is dedicated to addressing questions from the audience.