ASCVD

Video Library

  • Video Library

    World Heart Federation Roadmap

    In this video, Prof. Christopher Cannon provides a comprehensive overview of our infographic on the World Heart Foundation’s Cholesterol Roadmap (2022) for the management and prevention of atherosclerotic cardiovascular disease (ASCVD). He discusses various approaches for ASCVD prevention, emphasizes regional differences in adherence to ASCVD treatment guidelines, and highlights barriers to effective risk management. This roadmap offers a scientifically sound foundation for policymakers to implement changes aimed at reducing the burden of ASCVD.

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  • Running time: 35 minutes, 49 seconds

     

    00.16 Lp(a) structure and metabolism

    01.51 Elevated Lp(a) prevalence and risk of cardiovascular diseases

    02.38 Factors influencing Lp(a) level

    03.35 Physiological functions of Lp(a)

    04.12 Atherogenicity of Lp(a)

    04.56 Clinical implication of Lp(a) elevation

    05.25 Genetic variants associated with increased Lp(a) concentrations

    05.44 Association between high Lp(a) level and risk of various cardiovascular diseases

    07.43 Clinical implication of Lp(a) elevation at low LDL-C

    08.47 Lp(a) categories increases absolute baseline risk of traditional risk factors

    09.40 Is reducing Lp(a) physiologically safe?

    10.34 Strategies to lower Lp(a) level

    11.57 Future directions in Lp(a) research

    12.37 Summary

    Video Library

    Lp(a):What is it and its role in atherosclerosis

    In this video, Prof. Lale Tokgozoglu of Hacettepe University, former president of the European Atherosclerosis Society, discusses the structure, function, and genetics of Lp(a) and highlights the clinical implications of elevated Lp(a) levels. Using evidence from contemporary clinical studies, Prof. Tokgozoglu shares insights into approaches for lowering Lp(a) levels. Finally, challenges in the comprehensive understanding of the physiological and clinical implications of Lp(a) are discussed. Learning outcome – High levels of lipoprotein(a) increase the chances of experiencing heart attack, stroke, and aortic stenosis.

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Infographics

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Articles

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Case Studies

  • Case Studies

    August 2023

    Take this short quiz to test your knowledge on the recently published debate on dyslipidemias titled “Great debate: lipid-lowering therapies should be guided by vascular imaging rather than by circulating biomarkers”.

    CLICK HERE TO VIEW THE DEBATE.

    Eur Heart J. 2023 Jul 1;44(25):2292-2304. doi: 10.1093/eurheartj/ehad275

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  • Case Studies

    Quiz of the month – May 2023

    Take this short quiz to test your knowledge on some of the latest peer-reviewed published literature related to ASCVD and Lipidology.

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  • Case Studies

    Quiz of the month – April 2023

    Take our patient case study quiz specially curated for you by our Faculty Member, Prof. Samer Ellahham.

    Case Study: A 65-year-old man with a history of dyslipidemia, type 2 diabetes mellitus and systemic hypertension.

     

    Presentation:

    New onset crescendo angina x 5 days culminating

    Rest pain for the past 2h

    No history of other vascular events or heart attack, no TIA or stroke

    Weight: 90 kg

    Exam: BP 150/85 (slightly elevated), Heart Rate 80

    No murmur detected

     

    Medication:

    Valsartan 160 mg daily, Aspirin 81 mg daily, Rosuvastatin 10 mg daily, Metformin 500 mg twice daily

     

    Labs:

    BMI 31kg/m2, waist circumference 101.6 cm (40 inches), (-) tobacco (quit last year – 60-pack-year history)

    Normal CBC, electrolytes

    Troponin: Elevated

    Electrocardiogram:1-2 mm horizontal ST depression infero-lateral leads

    Chest X-ray: Normal

     

    Lipid panel:

    Total cholesterol (TC) 192 mg/dL

    HDL-C 46 mg/dL

    Triglycerides 180 mg/dL (non-fasting)

    LDL-C 110 mg/dL

    Non-HDL-C 146 mg/ dL

     

    What are the first impressions about this patient?

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